A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51)

DUI

D019377 MeSH Browser

CUI

M0028832

Previous indexing

Arachidonic Acids (1975-1984); Fatty Alcohols (1975-1976); Hydroxy Acids (1976-1978); Hydroxyeicosatetraenoic Acids (1985-1996)

History note

97; was 12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID (NM) 1975-96

Online note

use 12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID (NM) to search 12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID 1980-96

Public note

97; 12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID was indexed under HYDROXYEICOSATETRAENOIC ACIDS 1985-96, ARACHIDONIC ACIDS 1975-84, HYDROXY ACIDS 1976-80, & FATTY ALCOHOLS 1975-76