Enzym zajišťující integraci virové DNA do genomu hostitelské buňky. I. je např. obsažena ve viru HIV (označuje se jako p34, produkt genu pol). (cit. Velký lékařský slovník online, 2016 http://lekarske.slovniky.cz/ )

Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate BACTERIOPHAGES, the best known being BACTERIOPHAGE LAMBDA.

Anotace

HIV INTEGRASE is also available

DUI

D019426 MeSH Prohlížeč

CUI

M0028900

Předchozí užití

Coliphages/enzymology (1974-1980); DNA Helicases (1974-1987); DNA Nucleotidyltransferases (1974-1996); Viral Proteins (1980-1987)

Historická pozn.

2004(1997); use INTEGRASE (NM) 1974-1996

Veřejná pozn.

2004; see INTEGRASE 1997-2003; INTEGRASE was indexed under DNA NUCLEOTIDYLTRANSFERASES 1974-96, DNA UNWINDING PROTEINS 1974-87, VIRAL PROTEINS 1980-87, & COLIPHAGES/enzymology 1974-80