2,3-Diphosphoglycerate [2,3-difosfoglycerát]
- Terms
-
2,3-bisfosfoglycerát
2,3-DPG
kyselina 2,3-difosfoglycerová
-
2,3-Bisphosphoglycerate
2,3-Diphosphoglycerate, (D)-Isomer
2,3-Diphosphoglyceric Acid
2,3-DPG
Glycerate 2,3-Bisphosphate
A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
- DUI
- D019794 MeSH Browser
- CUI
- M0029370
- Previous indexing
- Diphosphoglyceric Acids (1980-1997)
- History note
- 98; use 2,3-DIPHOSPHOGLYCERATE (NM) 1980-97
- Public note
- 98; 2,3-DIPHOSPHOGLYCERATE was indexed under DIPHOSPHOGLYCERIC ACIDS 1980-97
Combination
- analogs & derivatives
- Diphosphoglyceric Acids
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis 1
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UR
- urine
cyclic-2,3-diphosphoglycerate Chemical MeSH Browser
deoxyhaemoglobin-2,3-diphosphoglycerate complex Chemical MeSH Browser