Nicorandil [nikorandil]
- Terms
-
2-nikotinamidoethylnitrát
-
2-Nicotinamidethyl Nitrate
2-Nicotinamidoethyl Nitrate
Adancor
Dancor
Ikorel
SG-75
A derivative of the NIACINAMIDE that is structurally combined with an organic nitrate. It is a potassium-channel opener that causes vasodilatation of arterioles and large coronary arteries. Its nitrate-like properties produce venous vasodilation through stimulation of guanylate cyclase.
- DUI
- D020108 MeSH Browser
- CUI
- M0029846
- CAS
- 3-Pyridinecarboxamide, N-(2-(Nitroxy)ethyl)-
- Previous indexing
- Niacinamide/analogs & derivatives (1978-1998); Nitrates (1978-1982)
- History note
- 1999; use NICORANDIL (NM) 1978-1998
- Public note
- 1999; NICORANDIL was indexed under NIACINAMIDE 1983-1998 & NITRATES 1978-1982
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UR
- urine