A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)

DUI

D020110 MeSH Browser

CUI

M0029848

CAS

Guanidine, N''-cyano-N-4-pyridinyl-N'-(1,2,2-trimethylpropylmonohydrate), (+-)-

Previous indexing

Guanidines (1983-1998); Pyridines (1980-1982)

History note

99; use PINACIDIL (NM) 1980-98

Public note

99; PINACIDIL was indexed under GUANIDINES 1983-98 & PYRIDINES 1980-82