MPTP Poisoning [otrava MPTP]
- Terms
-
intoxikace MPTP
MPTP - otrava
neurotoxický syndrom MPTP
otrava methylphenyltetrahydropyridinem
striatální degenerace vyvolaná methylphenyltetrahydropyridinem
striatální degenerace vyvolaná MPTP
syndrom neurotoxicity - MPTP
-
MPTP Neurotoxicity Syndrome
MPTP-Induced Degeneration of the Striatum
MPTP-Induced Parkinsonism
Neurotoxicity Syndrome, MPTP
Poisoning, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
A condition caused by the neurotoxin MPTP which causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE, SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36(2):250-8)
- Annotation
- not for animal models of Parkinson disease induced by MPTP: index MPTP-INDUCED EXPERIMENTAL PARKINSONISM
- DUI
- D020267 MeSH Browser
- CUI
- M0328147
- Previous indexing
- 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/poisoning (1990-1999); Parkinson Disease, Secondary (1983-1999)
- History note
- 2000
- Public note
- 2000
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