Maximum Tolerated Dose [maximální tolerovaná dávka]

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Terms

Maximal Tolerated Dose
Maximally Tolerated Dose

Persistent link   https://www.medvik.cz/link/D020714
Definition

The highest dose of a biologically active agent given during a chronic study that will not reduce longevity from effects other than carcinogenicity. (from Lewis Dictionary of Toxicology, 1st ed)

DUI
D020714 MeSH Browser
CUI
M0328199
History note
2000
Public note
2000

E Analytical, Diagnostic and Therapeutic Techniques and Equipment
E05 Investigative Techniques 209
E05.940 Toxicity Tests 408
E05.940.150 Carcinogenicity Tests 134
E05.940.245 Cytotoxicity Tests, Immunologic 321
E05.940.350 Inhibitory Concentration 50 173
E05.940.402 Lethal Dose 50 214
E05.940.481 Maximum Tolerated Dose 52
E05.940.560 Mutagenicity Tests 441
E05.940.600 No-Observed-Adverse-Effect Level 44
E05.940.790 Toxicity Tests, Acute 52
E05.940.800 Toxicity Tests, Chronic 17
E05.940.850 Toxicity Tests, Subacute 1
E05.940.900 Toxicity Tests, Subchronic 12

G Phenomena and Processes
G07 Physiological Phenomena 176
G07.690 Pharmacological and Toxicological Phenomena 59
G07.690.936 Toxicological Phenomena 4
G07.690.936.500 Dose-Response Relationship, Drug 2 366
G07.690.936.563 Inhibitory Concentration 50 173
G07.690.936.625 Maximum Tolerated Dose 52
G07.690.936.750 No-Observed-Adverse-Effect Level 44

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