Sodium Channel Blockers [blokátory sodíkových kanálů]
topical
41
- Terms
-
inhibitory sodíkových kanálů
sodíkové kanály - blokátory
-
Channel Blockers, Sodium
Sodium Channel Blocker
Sodium Channel Inhibitor
Sodium Channel Inhibitors
Persistent link
https://www.medvik.cz/link/D026941
Definition
A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity.
- Annotation
- coordinate with DIURETICS if pertinent
- DUI
- D026941 MeSH Browser
- CUI
- M0379271
- Previous indexing
- Ion Channels (1982-1988); Sodium Channels/antagonists & inhibitors (1988-2001)
- History note
- 2002
- Public note
- 2002
Allowable subheadings
- AD
- administration & dosage 4
- AE
- adverse effects 3
- AN
- analysis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 1
- CL
- classification 1
- EC
- economics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 0
- PK
- pharmacokinetics 3
- PD
- pharmacology 13
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 5
- TO
- toxicity 0
- UR
- urine 0
...
Occurrences in Medvik records