DNA Topoisomerases [DNA-topoisomerasy]
- Terms
-
DNA-topoisomerázy
topoizomerázy
Enzymes that regulate the topology of DNA by actions such as breaking, relaxing, passing, and rejoining strands of DNA in cells. These enzymes are important components of the DNA replication system. They are classified by their substrate specificities. DNA TOPOISOMERASE I enzymes act on a single strand of DNA. DNA TOPOISOMERASE II enzymes act on double strands of DNA.
- DUI
- D026942 MeSH Browser
- CUI
- M0379272
- Previous indexing
- DNA Topoisomerase (1977-2001); DNA Topoisomerase (ATP-Hydrolysing) (1979-2001)
- History note
- 2002
- Public note
- 2002
Combination
- antagonists & inhibitors
- Topoisomerase Inhibitors
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- BI
- biosynthesis 1
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 2
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 4
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
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