alpha Karyopherins [alfa karyoferiny]

topical
1
Terms

karyoferin alfa

 

Importin-alpha
Karyopherin alpha
NLS Receptor
NLS-Binding Protein
NLSBP
Nuclear Localization Sequence Receptor
Nuclear Localization Signal-Binding Protein

Persistent link   https://www.medvik.cz/link/D028901
Definition

Nucleocytoplasmic transport molecules that bind to the NUCLEAR LOCALIZATION SIGNALS of cytoplasmic molecules destined to be imported into the CELL NUCLEUS. Once attached to their cargo they bind to BETA KARYOPHERINS and are transported through the NUCLEAR PORE COMPLEX. Inside the CELL NUCLEUS alpha karyopherins dissociate from beta karypherins and their cargo. They then form a complex with CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN and RAN GTP-BINDING PROTEIN which is exported to the CYTOPLASM.

DUI
D028901 MeSH Browser
CUI
M0240469
Previous indexing
Nuclear Proteins (1994-2001)
History note
2002; use ALPHA KARYOPHERINS (NM) 1994-2001; for IMPORTIN-ALPHA use KARYOPHERINS 1995-2001; for NLS-BINDING PROTEIN, NLSBP & NUCLEAR LOCALIZATION SIGNAL-BINDING PROTEIN use NOPP140 (NM) 1992-2001
Public note
2002; KARYOPHERIN ALPHA (now ALPHA KARYOPHERINS) was indexed under NUCLEAR PROTEINS 1994-2001; IMPORTIN-ALPHA was indexed under NUCLEAR PROTEINS 1995-2001; NLS-BINDING PROTEIN, NLSBP & NUCLEAR LOCALIZATION SIGNAL-BINDING PROTEIN were indexed under NUCLEAR PROTEINS & PHOSPHOPROTEINS 1992-2001

D Chemicals and Drugs
D12.776 Proteins 2 577
D12.776.157 Carrier Proteins 546
D12.776.157.530 Membrane Transport Proteins 207
D12.776.157.530.750.500 Karyopherins 9
D12.776.157.530.750.500.100 alpha Karyopherins 1
D12.776.157.530.750.500.249 beta Karyopherins 3
D12.776.157.530.750.500.624 Exportin 1 Protein 1
D12.776.543 Membrane Proteins 849
D12.776.543.585 Membrane Transport Proteins 207
D12.776.543.585.750.500 Karyopherins 9
D12.776.543.585.750.500.100 alpha Karyopherins 1
D12.776.543.585.750.500.249 beta Karyopherins 3
D12.776.543.585.750.500.624 Exportin 1 Protein 1
D12.776.660 Nuclear Proteins 452
D12.776.660.502 Karyopherins 9
D12.776.660.502.100 alpha Karyopherins 1
D12.776.660.502.500 beta Karyopherins 3
D12.776.660.502.750 Exportin 1 Protein 1

Cut15 protein, S pombe Chemical MeSH Browser

Imp1 protein, S pombe Chemical MeSH Browser

KPNA1 protein, human Chemical MeSH Browser

KPNA1 protein, mouse Chemical MeSH Browser

KPNA2 protein, human Chemical MeSH Browser

KPNA3 protein, human Chemical MeSH Browser

KPNA4 protein, human Chemical MeSH Browser

KPNA5 protein, human Chemical MeSH Browser

KPNA6 protein, human Chemical MeSH Browser

KPNA6 protein, mouse Chemical MeSH Browser

KPNA7 protein, human Chemical MeSH Browser

Kap-alpha3 protein, Drosophila Chemical MeSH Browser

Kpna2 protein, mouse Chemical MeSH Browser

Kpna6 protein, rat Chemical MeSH Browser

Kpna7 protein, mouse Chemical MeSH Browser

PKL-1c peptide Chemical MeSH Browser

importin alpha 3, mouse Chemical MeSH Browser

importin alpha4, mouse Chemical MeSH Browser

karyopherin alpha 2 Chemical MeSH Browser