RNA-Induced Silencing Complex [komplex RISC]
topical
3
- Terms
-
komplex umlčující geny indukovaný RNA
-
RISC Multicomponent Nuclease
Persistent link
https://www.medvik.cz/link/D034743
Definition
A multicomponent, ribonucleoprotein complex comprised of one of the family of ARGONAUTE PROTEINS and the guide strand of the one of the 20- to 30-nucleotide small RNAs. RISC cleaves specific RNAs, which are targeted for degradation by homology to these small RNAs. Functions in regulating gene expression are determined by the specific argonaute protein and small RNA including siRNA (RNA, SMALL INTERFERING), miRNA (MICRORNA), or piRNA (PIWI-INTERACTING RNA).
- DUI
- D034743 MeSH Browser
- CUI
- M0406104
- Previous indexing
- Endoribonucleases (2001-2002)
- History note
- 2003; use RNA-INDUCED SILENCING COMPLEX (NM) 2001-2002
- Public note
- 2003; RNA-INDUCED SILENCING COMPLEX was indexed under RIBONUCLEOPROTEINS 2001-2002
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 1
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.277.352.700.350.381
Eosinophil-Derived Neurotoxin
D12.776.157.725.500.914
SS-B Antigen
D12.776.664.962.500.914
SS-B Antigen