Complement Pathway, Mannose-Binding Lectin [lektinová dráha komplementu]

topical
7
Terms

lektinová cesta
lektinová cesta aktivace komplementu
lektinová dráha
lektinová dráha aktivace komplementu

 

Lectin-Complement Pathway
Mannan-Binding Lectin Complement Pathway
Mannan-Binding Lectin Pathway (Complement Activation)
Mannose-Binding Lectin Complement Pathway

Persistent link   https://www.medvik.cz/link/D037582
Definition

Complement activation triggered by the interaction of microbial POLYSACCHARIDES with serum MANNOSE-BINDING LECTIN resulting in the activation of MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. As in the classical pathway, MASPs cleave COMPLEMENT C4 and COMPLEMENT C2 to form C3 CONVERTASE (C4B2A) and the subsequent C5 CONVERTASE (C4B2A3B) leading to cleavage of COMPLEMENT C5 and assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX.

DUI
D037582 MeSH Browser
CUI
M0413109
Previous indexing
Complement Activation (1989-2002)
History note
2003
Public note
2003

Allowable subheadings

DE
drug effects 0
ES
ethics 0
GE
genetics 0
IM
immunology 3
PH
physiology 3
RE
radiation effects 0

G Phenomena and Processes
G01 Physical Phenomena 75
G02 Chemical Phenomena 307
G03 Metabolic Phenomena obsolete
G04 Cell Physiological Phenomena 514
G05 Genetic Phenomena 133
G06 Microbiological Phenomena 95
G07 Physiological Phenomena 175
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 16
G12 Immune System Phenomena 248
G12.274 Complement Activation 95
G12.274.695 Complement Pathway, Alternative 11
G12.274.698 Complement Pathway, Classical 6
G12.274.849 Complement Pathway, Mannose-Binding Lectin 7
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 147
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 129
G17 Mathematical Concepts 66

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