An angiopoietin that is closely related to ANGIOPOIETIN-1. It binds to the TIE-2 RECEPTOR without receptor stimulation and antagonizes the effect of ANGIOPOIETIN-1. However its antagonistic effect may be limited to cell receptors that occur within the vasculature. Angiopoietin-2 may therefore play a role in down-regulation of BLOOD VESSEL branching and sprouting.

DUI

D042702 MeSH Prohlížeč

CUI

M0277968

Předchozí užití

Angiogenesis Factor (2003); Proteins (1999-2002)

Historická pozn.

2004; use ANGIOPOIETIN-2 (NM) 1997-2003

Veřejná pozn.

2004; ANGIOPOIETIN-2 was indexed under PROTEINS 1999-2002 & ANGIOGENESIS FACTOR 2003