Methylmalonate-Semialdehyde Dehydrogenase (Acylating) [methylmalonát-semialdehyddehydrogenasa (acylační)]
- Terms
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metylmalonát-semialdehyddehydrogenáza (acylační)
MMSDH
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Methylmalonic-Semialdehyde Dehydrogenase (Acylating)
MMSA Dehydrogenase
MMSDH
An enzyme that plays a role in the VALINE; LEUCINE; and ISOLEUCINE catabolic pathways by catalyzing the oxidation of 2-methyl-3-oxopropanate to propanoyl-CoA using NAD+ as a coenzyme. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated BETA-ALANINE and 3-hydropropionic acid.
- DUI
- D050646 MeSH Browser
- CUI
- M0144948
- History note
- 2006(1987)
- Public note
- 2006; METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE (ACYLATING) was indexed under ALDEHYDE OXIDOREDUCTASES 1987-2005
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine