Complement C5b [komplement C5b]

topical
Terms

C5b Complement
Complement 5b
Complement Component 5b

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Definition

The larger fragment generated from the cleavage of C5 by C5 CONVERTASE that yields COMPLEMENT C5A and C5b (beta chain + alpha' chain, the residual alpha chain, bound by disulfide bond). C5b remains bound to the membrane and initiates the spontaneous assembly of the late complement components to form C5b-8-poly-C9, the MEMBRANE ATTACK COMPLEX.

DUI
D050776 MeSH Browser
CUI
M0105345
CAS
Complement C 5b
History note
2006 (1982)
Public note
2006; COMPLEMENT C5B was indexed under COMPLEMENT 5 1982-2005