Protein Kinase C-alpha [proteinkinasa C-alfa]
- Terms
-
proteinkináza C-alfa
serin-threoninkinasa PKC-alfa
serin-threoninkináza PKC-alfa
-
PKC-alpha Serine-Threonine Kinase
Protein Kinase C alpha
Protein Kinase C(alpha)
A cytoplasmic serine threonine kinase involved in regulating CELL DIFFERENTIATION and CELLULAR PROLIFERATION. Overexpression of this enzyme has been shown to promote PHOSPHORYLATION of BCL-2 PROTO-ONCOGENE PROTEINS and chemoresistance in human acute leukemia cells.
- DUI
- D051571 MeSH Browser
- CUI
- M0233036
- History note
- 2006(1999)
- Public note
- 2006; PROTEIN KINASE C ALPHA was indexed under PROTEIN KINASE C 2004-2006, & under ISOENZYMES 1999-2003
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis 1
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 2
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
PRKCA protein, human Chemical MeSH Browser
Prkca protein, mouse Chemical MeSH Browser