A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS and CHYLOMICRON REMNANTS. Apo C-III, synthesized in the liver, is an inhibitor of LIPOPROTEIN LIPASE. Apo C-III modulates the binding of chylomicron remnants and VLDL to receptors (RECEPTORS, LDL) thus decreases the uptake of triglyceride-rich particles by the liver cells and subsequent degradation. The normal Apo C-III is glycosylated. There are several polymorphic forms with varying amounts of SIALIC ACID (Apo C-III-0, Apo C-III-1, and Apo C-III-2).

DUI

D053305 MeSH Prohlížeč

CUI

M0073736

Předchozí užití

Apolipoproteins C (1977-2006)

Historická pozn.

2007; use APOLIPOPROTEIN C-III (NM) 1979-2006

Veřejná pozn.

2007; APOLIPOPROTEIN C-III was indexed under APOLIPOPROTEINS C 1985-2006 & under APOLIPOPROTEINS 1979-1984