Nod2 Signaling Adaptor Protein [signální adaptorový protein Nod2]
- Terms
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protein CARD15
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CARD15 Protein
Caspase Recruitment Domain Protein 15
Nucleotide Oligomerization Domain 2 Protein
A NOD signaling adaptor protein that contains two C-terminal leucine-rich domains which recognize bacterial PEPTIDOGLYCAN. It signals via an N-terminal capase recruitment domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE KINASES. The protein plays a role in the host defense response by signaling the activation of CASPASES and the MAP KINASE SIGNALING SYSTEM. Mutations of the gene encoding the nucleotide oligomerization domain 2 protein have been associated with increased susceptibility to CROHN DISEASE.
- DUI
- D053473 MeSH Browser
- CUI
- M0493385
- Previous indexing
- Carrier Proteins (2001-2004); Intracellular Signaling Peptides and Proteins (2005-2006)
- History note
- 2007
- Public note
- 2007
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects 1
- EC
- economics
- GE
- genetics 16
- HI
- history
- IM
- immunology 4
- IP
- isolation & purification
- ME
- metabolism 3
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
NOD2 protein, human Chemical MeSH Browser
NOD2 protein, rat Chemical MeSH Browser
NOD2 protein, zebrafish Chemical MeSH Browser
Nod2 protein, mouse Chemical MeSH Browser