Protein Tyrosine Phosphatase, Non-Receptor Type 22 [tyrosinfosfatasa nereceptorového typu 22]

topical
12
Terms

Lyp1 PTPasa
Lyp2 PTPasa
protein PTPN-22
protein-tyrosinfosfatasa nereceptorového typu 22
PTPasa Lyp
PTPasa Lyp1
PTPasa Lyp2
PTPáza Lyp
tyrosin specifická proteinfosfatasa nereceptorového typu 22
tyrosinová proteinfosfatasa nereceptorového typu 22
tyrozinfosfatáza nereceptorového typu 22

 

Lymphoid Phosphatase
Lyp1 PTPase
Lyp2 PTPase
Protein-Tyrosine Phosphatase Lyp
PTPase Lyp
PTPN-22 Protein
Tyrosine Protein Phosphatase, Non-Receptor Type 22

Persistent link   https://www.medvik.cz/link/D054596
Definition

A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an N-terminal catalytic domain and a C-terminal PROLINE-rich domain. The phosphatase subtype is predominantly expressed in LYMPHOCYTES and plays a key role in the inhibition of downstream T-LYMPHOCYTE activation. Polymorphisms in the gene that encodes this phosphatase subtype are associated with a variety of AUTOIMMUNE DISEASES.

DUI
D054596 MeSH Browser
CUI
M0302581
History note
2008(1999)
Public note
2008; TYROSINE PROTEIN PROSPHATASE, NON-RECEPTOR TYPE 22 was indexed under PROTEIN TYROSINE PHOSPHATASES 1999-2007

D Chemicals and Drugs
D08.811 Enzymes 1 547
D08.811.277 Hydrolases 475
D08.811.277.352 Esterases 207
D08.811.277.352.650 Phosphoric Monoester Hydrolases 154
D08.811.277.352.650.775 Protein Tyrosine Phosphatases 27
D08.811.277.352.650.775.300 Protein Tyrosine Phosphatases, Non-Receptor 4
D08.811.277.352.650.775.300.100 Protein Tyrosine Phosphatase, Non-Receptor Type 1 3
D08.811.277.352.650.775.300.200 Protein Tyrosine Phosphatase, Non-Receptor Type 2 3
D08.811.277.352.650.775.300.600 Protein Tyrosine Phosphatase, Non-Receptor Type 6 5
D08.811.277.352.650.775.300.930 Protein Tyrosine Phosphatase, Non-Receptor Type 22 12
D12.776 Proteins 2 577

PTPN22 protein, human Chemical MeSH Browser

PTPN22 protein, rat Chemical MeSH Browser

Ptpn22 protein, mouse Chemical MeSH Browser