Telomere Shortening [zkracování telomer]

topical
35
Persistent link   https://www.medvik.cz/link/D059506
Definition

The loss of some TELOMERE sequence during DNA REPLICATION of the first several base pairs of a linear DNA molecule; or from DNA DAMAGE. Cells have various mechanisms to restore length (TELOMERE HOMEOSTASIS.) Telomere shortening is involved in the progression of CELL AGING.

DUI
D059506 MeSH Browser
CUI
M0550398
Previous indexing
Telomere (1992-2011)
History note
2012
Public note
2012

Allowable subheadings

DE
drug effects 6
GE
genetics 7
IM
immunology 0
PH
physiology 8
RE
radiation effects 0

G Phenomena and Processes
G02 Chemical Phenomena 307
G02.111 Biochemical Phenomena 370
G02.111.225 DNA Replication 287
G02.111.225.380 DNA Damage Tolerance
G02.111.225.760 DNA Replication Timing 3
G02.111.225.880 S Phase 81
G02.111.225.940 Telomere Shortening 35
G04 Cell Physiological Phenomena 514
G04.043 Cellular Senescence 230
G04.043.260 Erythrocyte Aging 21
G04.043.445 Senescence-Associated Secretory Phenotype 2
G04.043.538 T-Cell Senescence
G04.043.630 Telomere Shortening 35
G05 Genetic Phenomena 135
G05.226 DNA Replication 287
G05.226.380 DNA Damage Tolerance
G05.226.760 DNA Replication Timing 3
G05.226.820 Endoreduplication 6
G05.226.880 S Phase 81
G05.226.940 Telomere Shortening 35
G07 Physiological Phenomena 176
G07.345 Growth and Development 246
G07.345.124 Aging 4 012
G07.345.124.130 Cellular Senescence 230
G07.345.124.130.260 Erythrocyte Aging 21
G07.345.124.130.445 Senescence-Associated Secretory Phenotype 2
G07.345.124.130.630 Telomere Shortening 35

Add