Antibodies, Monoclonal, Humanized [humanizované monoklonální protilátky]
topical
2 757
- Terms
-
humánní monoklonální protilátky
monoklonální protilátky humanizované
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Antibodies, Humanized
Persistent link
https://www.medvik.cz/link/D061067
Definition
Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab.
- DUI
- D061067 MeSH Browser
- CUI
- M0556300
- Previous indexing
- Antibodies, Monoclonal (1991-2011)
- History note
- 2012
- Public note
- 2012
Allowable subheadings
- AD
- administration & dosage 1 042
- AE
- adverse effects 595
- AN
- analysis 4
- BI
- biosynthesis 0
- BL
- blood 5
- CF
- cerebrospinal fluid 1
- CH
- chemistry 6
- CL
- classification 76
- DE
- drug effects 11
- EC
- economics 55
- GE
- genetics 0
- HI
- history 0
- IM
- immunology 34
- IP
- isolation & purification 0
- ME
- metabolism 3
- PK
- pharmacokinetics 149
- PD
- pharmacology 676
- PH
- physiology 0
- PO
- poisoning 1
- RE
- radiation effects 0
- TU
- therapeutic use 1 996
- TO
- toxicity 6
- UL
- ultrastructure 1
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs