Central Tolerance [centrální tolerance]

topical
2
Persistent link   https://www.medvik.cz/link/D061167
Definition

The mechanism, in central lymphoid organs (THYMUS; BONE MARROW), that prevents immature lymphocytes from reacting to SELF-ANTIGENS. This is accomplished by CLONAL ANERGY and CLONAL DELETION.

DUI
D061167 MeSH Browser
CUI
M0556537
Previous indexing
Immune Tolerance (1980-2011); Self Tolerance (1998-2011)
History note
2012
Public note
2012

Allowable subheadings

DE
drug effects 0
GE
genetics 0
IM
immunology 0
PH
physiology 0
RE
radiation effects 0

G Phenomena and Processes
G01 Physical Phenomena 77
G02 Chemical Phenomena 307
G03 Metabolic Phenomena obsolete
G04 Cell Physiological Phenomena 514
G05 Genetic Phenomena 135
G06 Microbiological Phenomena 96
G07 Physiological Phenomena 176
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 16
G12 Immune System Phenomena 248
G12.535 Immunomodulation 514
G12.535.425 Immune Tolerance 349
G12.535.425.800 Self Tolerance 12
G12.535.425.800.200 Central Tolerance 2
G12.535.425.800.600 Peripheral Tolerance 1
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 147
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 129
G17 Mathematical Concepts 66

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