Lopinavir [Lopinavir]

topical
10
Terms

A-157378.0
ABT 378
ABT-378
N-(4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pydrimidineacetamide

Persistent link   https://www.medvik.cz/link/D061466
Definition

An HIV protease inhibitor used in a fixed-dose combination with RITONAVIR. It is also an inhibitor of CYTOCHROME P-450 CYP3A.

DUI
D061466 MeSH Browser
CUI
M0558541
History note
2012
Public note
2012; LOPNAVIR was indexed under PYRIMIDINONES 2000-2011