Lopinavir [Lopinavir]
- Terms
-
A-157378.0
ABT 378
ABT-378
N-(4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pydrimidineacetamide
An HIV protease inhibitor used in a fixed-dose combination with RITONAVIR. It is also an inhibitor of CYTOCHROME P-450 CYP3A.
- DUI
- D061466 MeSH Browser
- CUI
- M0558541
- History note
- 2012
- Public note
- 2012; LOPNAVIR was indexed under PYRIMIDINONES 2000-2011
Allowable subheadings
- AD
- administration & dosage 2
- AE
- adverse effects 2
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology 2
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 4
- TO
- toxicity
- UR
- urine
lopinavir-ritonavir drug combination Chemical MeSH Browser