Polycomb Repressive Complex 2 [PRC2]

topical
4
Terms

represivní komplex Polycomb 2

Persistent link   https://www.medvik.cz/link/D063151
Definition

A multisubunit polycomb protein complex that catalyzes the METHYLATION of chromosomal HISTONE H3. It works in conjunction with POLYCOMB REPRESSIVE COMPLEX 1 to effect EPIGENETIC REPRESSION.

DUI
D063151 MeSH Browser
CUI
M0499463
Previous indexing
Repressor Proteins (1998-2012); Transcription Factors (1997)
History note
2013
Public note
2013

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics 3
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 3
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D05 Macromolecular Substances 103
D05.500 Multiprotein Complexes 65
D05.500.781 Polycomb-Group Proteins 7
D05.500.781.100 Polycomb Repressive Complex 1 6
D05.500.781.750 Polycomb Repressive Complex 2 4
D05.500.781.750.250 Enhancer of Zeste Homolog 2 Protein 6
D05.500.781.750.500 Retinoblastoma-Binding Protein 4
D05.500.781.750.750 Retinoblastoma-Binding Protein 7
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 549
D08.811.913 Transferases 72
D08.811.913.555 One-Carbon Group Transferases
D08.811.913.555.500 Methyltransferases 93
D08.811.913.555.500.800 Protein Methyltransferases 2
D08.811.913.555.500.800.200 Histone Methyltransferases 2
D08.811.913.555.500.800.200.500 Histone-Lysine N-Methyltransferase 56
D08.811.913.555.500.800.200.500.500 Polycomb Repressive Complex 2 4
D08.811.913.555.500.800.200.500.500.500 Enhancer of Zeste Homolog 2 Protein 6
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 579
D12.776.660 Nuclear Proteins 455
D12.776.660.235 Chromosomal Proteins, Non-Histone 93
D12.776.660.235.600 Polycomb-Group Proteins 7
D12.776.660.235.600.100 Polycomb Repressive Complex 1 6
D12.776.660.235.600.200 Polycomb Repressive Complex 2 4
D12.776.660.235.600.200.250 Enhancer of Zeste Homolog 2 Protein 6
D12.776.660.235.600.200.500 Retinoblastoma-Binding Protein 4
D12.776.660.235.600.200.750 Retinoblastoma-Binding Protein 7
D12.776.664 Nucleoproteins 91
D12.776.664.235 Chromosomal Proteins, Non-Histone 93
D12.776.664.235.800 Polycomb-Group Proteins 7
D12.776.664.235.800.100 Polycomb Repressive Complex 1 6
D12.776.664.235.800.200 Polycomb Repressive Complex 2 4
D12.776.664.235.800.200.250 Enhancer of Zeste Homolog 2 Protein 6
D12.776.664.235.800.200.500 Retinoblastoma-Binding Protein 4
D12.776.664.235.800.200.750 Retinoblastoma-Binding Protein 7
D12.776.930 Transcription Factors 733
D12.776.930.780 Repressor Proteins 189
D12.776.930.780.890 Polycomb-Group Proteins 7
D12.776.930.780.890.100 Polycomb Repressive Complex 1 6
D12.776.930.780.890.200 Polycomb Repressive Complex 2 4
D12.776.930.780.890.200.250 Enhancer of Zeste Homolog 2 Protein 6
D12.776.930.780.890.200.500 Retinoblastoma-Binding Protein 4
D12.776.930.780.890.200.750 Retinoblastoma-Binding Protein 7

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