A 23-year-old, HIV-negative woman who had undergone a hematopoietic stem cell transplantation was admitted to the hospital with respiratory failure and symptoms of bronchiolitis obliterans. A chest computed tomography scan revealed diffuse ground-glass opacification and fibrous plugs. Due to worsening respiratory failure despite treatment, ventilation was provided through a tracheostomy tube. Molecular examination of bronchoalveolar lavage and urine revealed Enterocytozoon bieneusi infection. After treatment with albendazole the patient gradually improved, but the pathogen was not eradicated and reappeared on follow-up examination. E. bieneusi belongs to the most clinically important microsporidial species infecting humans, mostly those who are immunocompromised. This fungus tends to infect enterocytes of the intestine, and there are limited studies concerning its extraintestinal location. This is the first report of a case of disseminated respiratory and urinary E. bieneusi infection in a transplant recipient.

• MeSH
• albendazol terapeutické užití   MeSH
• bronchoalveolární laváž MeSH
• Enterocytozoon účinky léků   izolace a purifikace   MeSH
• HIV infekce MeSH
• hostitel s imunodeficiencí účinky léků   MeSH
• infekce močového ústrojí diagnóza   farmakoterapie   MeSH
• levofloxacin terapeutické užití   MeSH
• lidé MeSH
• mikrosporidióza diagnóza   farmakoterapie   MeSH
• mladý dospělý MeSH
• rizikové faktory MeSH
• transplantace hematopoetických kmenových buněk * MeSH
• Check Tag
• lidé MeSH
• mladý dospělý MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• kazuistiky MeSH