Lymphogranuloma venereum (LGV) is an infection caused by a subspecies of the bacterium Chlamydia trachomatis (invasive serovars L1, L2, or L3). It primarily causes painful swelling of the lymph nodes located closest to the site of initial infection. If untreated, the disease can progress and patients are needed in order to better consider the statements presented in this article. If untreated, it causes serious skin damages like scarring and genital elephantiasis. LGV is transmitted by direct sexual contact with genitals, rectum, or mouth. Once in the body, Chlamydia Spp. could reproduce themselves in the lymph nodes and could spread to other organs, provoking complications, such as the so-called pelvic inflammatory disease. Both genital and extragenital manifestations of this disease are able to induce serious differential diagnostic difficulties, indirectly leading to progression and dissemination of the infection. The reason for that might be – not very rarely – related to non-typical clinical and histopathological findings. This article presents two unusual cases of LGV with atypical histopathological/clinical findings and also focuses on alternative therapeutical approaches, such as surgical excision at stage 1, leading to positive outcome. However, the question if the surgical method could be used as a standard therapy at stage 1 remains open for discussion. It is not completely clear either if histopathological findings of LGV could reveal progress and/or changes through time as it happens in other diseases like pyoderma gangrenosum. We conclude that both histological and clinical observation on a larger number of patients is needed in order to better consider the statements presented in this article.
- MeSH
- antibakteriální látky terapeutické užití MeSH
- Chlamydia trachomatis izolace a purifikace patogenita MeSH
- chlamydiové infekce diagnóza patofyziologie přenos MeSH
- diferenciální diagnóza MeSH
- dospělí MeSH
- doxycyklin aplikace a dávkování terapeutické užití MeSH
- histologické techniky MeSH
- homosexualita mužská MeSH
- lidé MeSH
- lymfatické uzliny chirurgie mikrobiologie patofyziologie MeSH
- lymphogranuloma venereum diagnóza farmakoterapie mikrobiologie MeSH
- nemoci penisu diagnóza farmakoterapie MeSH
- přenos infekční nemoci MeSH
- senioři nad 80 let MeSH
- sexuálně přenosné nemoci MeSH
- stupeň závažnosti nemoci MeSH
- ústa MeSH
- výsledek terapie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- Publikační typ
- kazuistiky MeSH
- přehledy MeSH
- MeSH
- balónková koronární angioplastika trendy MeSH
- diagnostické techniky kardiovaskulární trendy MeSH
- diagnostické zobrazování metody trendy MeSH
- koronární cévy chirurgie patologie MeSH
- lidé MeSH
- nemoci koronárních tepen diagnóza chirurgie MeSH
- ultrazvuk MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- srovnávací studie MeSH
- MeSH
- gentamiciny farmakokinetika MeSH
- monitorování léčiv metody využití MeSH
- Publikační typ
- přehledy MeSH
