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Autor
Curila, Karol 1 Halamek, Josef 1 Heckman, Luuk 1 Jastrzebski, Marek 1 Jurak, Pavel 1 Karch, Jakub 1 Leinveber, Pavel 1 Mizner, Jan 1 Moskal, Pawel 1 Osmancik, Pavel 1 Plesinger, Filip 1 Prinzen, Frits 1 Smisek, Radovan 1 Susankova, Marketa 1 Vernooy, Kevin 1 Viscor, Ivo 1 Vondra, Vlastimil 1 Waldauf, Petr 1 Znojilova, Lucie 1
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Pracoviště
1st Department of Cardiology Interven... 1 Cardiocenter 3rd Faculty of Medicine ... 1 Department of Anesthesia and Intensiv... 1 Department of Biomedical Engineering ... 1 Department of Cardiology Cardiovascul... 1 Department of Physiology Cardiovascul... 1 International Clinical Research Cente... 1 The Czech Academy of Sciences Institu... 1
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Autor
Curila, Karol 1 Halamek, Josef 1 Heckman, Luuk 1 Jastrzebski, Marek 1 Jurak, Pavel 1 Karch, Jakub 1 Leinveber, Pavel 1 Mizner, Jan 1 Moskal, Pawel 1 Osmancik, Pavel 1 Plesinger, Filip 1 Prinzen, Frits 1 Smisek, Radovan 1 Susankova, Marketa 1 Vernooy, Kevin 1 Viscor, Ivo 1 Vondra, Vlastimil 1 Waldauf, Petr 1 Znojilova, Lucie 1
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Pracoviště
1st Department of Cardiology Interven... 1 Cardiocenter 3rd Faculty of Medicine ... 1 Department of Anesthesia and Intensiv... 1 Department of Biomedical Engineering ... 1 Department of Cardiology Cardiovascul... 1 Department of Physiology Cardiovascul... 1 International Clinical Research Cente... 1 The Czech Academy of Sciences Institu... 1
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PubMed Central od 2014
Europe PubMed Central od 2014
Open Access Digital Library od 2014-01-01
Open Access Digital Library od 2014-01-01
ROAD: Directory of Open Access Scholarly Resources od 2014
PubMed
34950718
DOI
10.3389/fcvm.2021.787414
Knihovny.cz E-zdroje
Background: Three different ventricular capture types are observed during left bundle branch pacing (LBBp). They are selective LBB pacing (sLBBp), non-selective LBB pacing (nsLBBp), and myocardial left septal pacing transiting from nsLBBp while decreasing the pacing output (LVSP). Study aimed to compare differences in ventricular depolarization between these captures using ultra-high-frequency electrocardiography (UHF-ECG). Methods: Using decremental pacing voltage output, we identified and studied nsLBBp, sLBBp, and LVSP in patients with bradycardia. Timing of ventricular activations in precordial leads was displayed using UHF-ECGs, and electrical dyssynchrony (e-DYS) was calculated as the difference between the first and last activation. The durations of local depolarizations (Vd) were determined as the width of the UHF-QRS complex at 50% of its amplitude. Results: In 57 consecutive patients, data were collected during nsLBBp (n = 57), LVSP (n = 34), and sLBBp (n = 23). Interventricular dyssynchrony (e-DYS) was significantly lower during LVSP -16 ms (-21; -11), than nsLBBp -24 ms (-28; -20) and sLBBp -31 ms (-36; -25). LVSP had the same V1d-V8d as nsLBBp and sLBBp except for V3d, which during LVSP was shorter than sLBBp; the mean difference -9 ms (-16; -1), p = 0.01. LVSP caused less interventricular dyssynchrony and the same or better local depolarization durations than nsLBBp and sLBBp irrespective of QRS morphology during spontaneous rhythm or paced QRS axis. Conclusions: In patients with bradycardia, LVSP in close proximity to LBB resulted in better interventricular synchrony than nsLBBp and sLBBp and did not significantly prolong depolarization of the left ventricular lateral wall.
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