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Autor
Benovska, Miroslava 1 Boucek, Lubos 1 Buckova, Dana 1 Demlova, Regina 1 Horska, Katerina 1 Korberova, Alena 1 Kozakova, Sarka 1 Mikuskova, Alena 1 Podborska, Martina 1 Radina, Martin 1 Richter, Michal 1 Rihacek, Michal 1 Selingerova, Iveta 1 Starha, Jiri 1 Valik, Dalibor 1 Wiewiorka, Ondrej 1 Zdrazilova Dubska, Lenka 1
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Pracoviště
Department of Laboratory Medicine Uni... 1 Department of Laboratory Medicine Uni... 1 Department of Laboratory Methods Facu... 1 Department of Mathematics and Statist... 1 Department of Pediatric Hematology an... 1 Department of Pediatric Oncology Univ... 1 Department of Pediatrics Pediatric Ne... 1 Department of Pharmacology Faculty of... 1 Department of Pharmacology and Toxico... 1 Department of Pharmacy Clinical Pharm... 1 Department of Pharmacy University Hos... 1 Diagnostic and Therapeutic Centre Eme... 1 Faculty of Medicine Masaryk Universit... 1 General Teaching Hospital Prague Czechia 1 Research Unit for Rare Diseases Depar... 1 Spadia Laboratories Central Reference... 1
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Autor
Benovska, Miroslava 1 Boucek, Lubos 1 Buckova, Dana 1 Demlova, Regina 1 Horska, Katerina 1 Korberova, Alena 1 Kozakova, Sarka 1 Mikuskova, Alena 1 Podborska, Martina 1 Radina, Martin 1 Richter, Michal 1 Rihacek, Michal 1 Selingerova, Iveta 1 Starha, Jiri 1 Valik, Dalibor 1 Wiewiorka, Ondrej 1 Zdrazilova Dubska, Lenka 1
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Pracoviště
Department of Laboratory Medicine Uni... 1 Department of Laboratory Medicine Uni... 1 Department of Laboratory Methods Facu... 1 Department of Mathematics and Statist... 1 Department of Pediatric Hematology an... 1 Department of Pediatric Oncology Univ... 1 Department of Pediatrics Pediatric Ne... 1 Department of Pharmacology Faculty of... 1 Department of Pharmacology and Toxico... 1 Department of Pharmacy Clinical Pharm... 1 Department of Pharmacy University Hos... 1 Diagnostic and Therapeutic Centre Eme... 1 Faculty of Medicine Masaryk Universit... 1 General Teaching Hospital Prague Czechia 1 Research Unit for Rare Diseases Depar... 1 Spadia Laboratories Central Reference... 1
- Formát
- Publikační typ
- Kategorie
- Jazyk
- Země
- Časopis/zdroj
- Dostupnost
- Vlastník
- Demlova, Regina
- Kozakova, Sarka
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Rihacek, Michal
Autor Rihacek, Michal Diagnostic and Therapeutic Centre, Emergency Services Department, University Hospital Brno, Masaryk University, Brno, Czechia Department of Laboratory Medicine, University Hospital Brno, Masaryk University, Brno, Czechia Department of Laboratory Methods, Faculty of Medicine, Masaryk University, Brno, Czechia
- Buckova, Dana
- Horska, Katerina
- Wiewiorka, Ondrej
- Boucek, Lubos
- Selingerova, Iveta
- Podborska, Martina
- Korberova, Alena
NLK
Directory of Open Access Journals
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od 2014
PubMed
38259831
DOI
10.3389/fmed.2023.1236948
Knihovny.cz E-zdroje
BACKGROUND: Assessment of kidney function in emergency settings is essential across all medical subspecialties. Daily assessment of patient creatinine results from emergency medical services showed that some deviated from expected values, implying drug-related interference. METHODS: Real-time clinical evaluation of an enzyme method (Roche CREP2) in comparison with the Jaffé gen. 2 method (Roche CREJ2) was performed. During the period of December 2022 and January 2023, we analyzed 8,498 patient samples, where 5,524 were heavily medicated STAT patient specimens, 500 were pediatric specimens, and 2,474 were from a distant general population in a different region using the same methods. RESULTS: In 109 out of 5,524 hospital specimens (1.97%, p < 0.001), the CREP2 value was apparently (25% or more) lower than CREJ2. Suspect interfering medication was found in a sample of 43 out of 46 reviewed patients where medication data were available. This phenomenon was not observed in the general population. CONCLUSION: In a polymedicated urgent care hospital population, a creatinine enzyme method produces unreliable results, apparently due to multiple drug-related interferences.
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Po ukončení testovacího provozu bude odkaz přesměrován adresu produkční verze portálu Medvik.