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Department of Pathology Brigham and W... 1 Department of Psychiatry Semel Instit... 1 Division of Infectious Diseases Brigh... 1 Division of Otolaryngology Department... 1 Division of Plastic Surgery Departmen... 1 Schuster Transplantation Research Cen... 1 Speech and Feeding Disorders Lab MGH ... 1
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Pracoviště
Department of Pathology Brigham and W... 1 Department of Psychiatry Semel Instit... 1 Division of Infectious Diseases Brigh... 1 Division of Otolaryngology Department... 1 Division of Plastic Surgery Departmen... 1 Schuster Transplantation Research Cen... 1 Speech and Feeding Disorders Lab MGH ... 1
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- Kauke, Martin
- Panayi, Adriana C
- Safi, Ali-Farid
- Haug, Valentin
- Perry, Bridget
- Kollar, Branislav
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Nizzi, Marie-Christine
Autor Nizzi, Marie-Christine Division of Plastic Surgery, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA Department of Psychiatry, Semel Institute for Neuroscience and Human Behavior, Geffen School of Medicine at UCLA, Los Angeles, California, USA
- Broyles, Justin
- Annino, Donald J
- Marty, Francisco M
NLK
Free Medical Journals
od 2001 do 2022
Elsevier Open Access Journals
od 2001-05-01 do Před 1 rokem
ROAD: Directory of Open Access Scholarly Resources
od 2001
PubMed
34033210
DOI
10.1111/ajt.16696
Knihovny.cz E-zdroje
There is limited experience with facial retransplantation (fRT). We report on the management of facial retransplantation in a facial vascularized composite allotransplant recipient following irreversible allograft loss 88 months after the first transplant. Chronic antibody-mediated rejection and recurrent cellular rejection resulted in a deteriorated first allograft and the patient underwent retransplantation. We summarize the events between the two transplantations, focusing on the final rejection episode. We describe the surgical technique of facial retransplantation, the immunological and psychosocial management, and the 6-month postoperative outcomes. Removal of the old allograft and inset of the new transplant were done in one operation. The donor and recipient were a good immunological match. The procedure was technically complex, requiring more proximal arterial anastomoses and an interposition vein graft. During the first and second transplantation, the facial nerve was coapted at the level of the branches. There was no hyperacute rejection in the immediate postoperative phase. Outcomes 6 months postoperatively are promising. We provide proof-of-concept that facial retransplantation is a viable option for patients who suffer irreversible facial vascularized composite allograft loss.
- MeSH
- homologní transplantace MeSH
- lidé MeSH
- rejekce štěpu * etiologie MeSH
- reoperace MeSH
- štěpy z kompozitní tkáně * MeSH
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- lidé MeSH
- ženské pohlaví MeSH
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- kazuistiky MeSH
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