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Autor
Agudo-Barriuso, Marta 1 Antica, Mariastefania 1 Couto, Pedro Silva 1 Dubus, Marie 1 Forostyak, Serhiy 1 Gindraux, Florelle 1 Girandon, Lenart 1 Gramignoli, Roberto 1 Hofmann, Nicola 1 Jurga, Marcin 1 Lafarge, Xavier 1 Liarte, Sergio 1 Navakauskiene, Ruta 1 Nicolás, Francisco J 1 Shablii, Volodymyr 1
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Pracoviště
Biomatériaux et Inflammation en Site ... 1 Department of Biochemical Engineering... 1 Department of Burns and Plastic Surge... 1 Department of Laboratory Medicine Div... 1 Department of Molecular Cell Biology ... 1 Division of Molecular Biology Rudjer ... 1 EXO Biologics Liege Belgium 1 Educell ltd Trzin Slovenia 1 Experimental Ophthalmology Group Univ... 1 German Society for Tissue Transplanta... 1 Laboratoire de Nanomédecine Imagerie ... 1 Laboratory of Biosynthesis of Nucleic... 1 Placenta Stem Cell Laboratory Cryoban... 1 PrimeCell Bioscience Ostrava Czech Re... 1 Regeneration Molecular Oncology and T... 1 Service de Chirurgie Orthopédique Tra... 1 Établissement Français du Sang Nouvel... 1
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Autor
Agudo-Barriuso, Marta 1 Antica, Mariastefania 1 Couto, Pedro Silva 1 Dubus, Marie 1 Forostyak, Serhiy 1 Gindraux, Florelle 1 Girandon, Lenart 1 Gramignoli, Roberto 1 Hofmann, Nicola 1 Jurga, Marcin 1 Lafarge, Xavier 1 Liarte, Sergio 1 Navakauskiene, Ruta 1 Nicolás, Francisco J 1 Shablii, Volodymyr 1
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Pracoviště
Biomatériaux et Inflammation en Site ... 1 Department of Biochemical Engineering... 1 Department of Burns and Plastic Surge... 1 Department of Laboratory Medicine Div... 1 Department of Molecular Cell Biology ... 1 Division of Molecular Biology Rudjer ... 1 EXO Biologics Liege Belgium 1 Educell ltd Trzin Slovenia 1 Experimental Ophthalmology Group Univ... 1 German Society for Tissue Transplanta... 1 Laboratoire de Nanomédecine Imagerie ... 1 Laboratory of Biosynthesis of Nucleic... 1 Placenta Stem Cell Laboratory Cryoban... 1 PrimeCell Bioscience Ostrava Czech Re... 1 Regeneration Molecular Oncology and T... 1 Service de Chirurgie Orthopédique Tra... 1 Établissement Français du Sang Nouvel... 1
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NLK
Directory of Open Access Journals
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Free Medical Journals
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PubMed Central
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Open Access Digital Library
od 2013-01-01
ROAD: Directory of Open Access Scholarly Resources
od 2013
PubMed
36304904
DOI
10.3389/fbioe.2022.977590
Knihovny.cz E-zdroje
Perinatal derivatives are drawing growing interest among the scientific community as an unrestricted source of multipotent stromal cells, stem cells, cellular soluble mediators, and biological matrices. They are useful for the treatment of diseases that currently have limited or no effective therapeutic options by means of developing regenerative approaches. In this paper, to generate a complete view of the state of the art, a comprehensive 10-years compilation of clinical-trial data with the common denominator of PnD usage has been discussed, including commercialized products. A set of criteria was delineated to challenge the 10-years compilation of clinical trials data. We focused our attention on several aspects including, but not limited to, treated disorders, minimal or substantial manipulation, route of administration, dosage, and frequency of application. Interestingly, a clear correlation of PnD products was observed within conditions, way of administration or dosage, suggesting there is a consolidated clinical practice approach for the use of PnD in medicine. No regulatory aspects could be read from the database since this information is not mandatory for registration. The database will be publicly available for consultation. In summary, the main aims of this position paper are to show possibilities for clinical application of PnD and propose an approach for clinical trial preparation and registration in a uniform and standardized way. For this purpose, a questionnaire was created compiling different sections that are relevant when starting a new clinical trial using PnD. More importantly, we want to bring the attention of the medical community to the perinatal products as a consolidated and efficient alternative for their use as a new standard of care in the clinical practice.
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Po ukončení testovacího provozu bude odkaz přesměrován adresu produkční verze portálu Medvik.