- MeSH
- androgeny metabolismus MeSH
- buněčná adheze MeSH
- gonadotropiny farmakologie MeSH
- Leydigovy buňky fyziologie účinky léků ultrastruktura MeSH
- luteinizační hormon farmakologie MeSH
- lymfocyty radiografie účinky záření virologie MeSH
- myši MeSH
- zvířata MeSH
- Check Tag
- mužské pohlaví MeSH
- myši MeSH
- zvířata MeSH
In the present paper we report on the study of the ultrastructure of Leydig cells of male mice after application of various doses of Pb(NO3)2 in drinking water for 2, 3, 4, 5, 7, 9 and 11 weeks. The increasing dose and time interval lead to formation of numerous concentric lamellar systems, accumulation of fatty vacuoles, vacuolization of mitochondria, pronounced surface differentiation, and changed shape of the nucleus of Leydig cells. The ultrastructural picture corresponded with an enhanced metabolic activity in some cells; in other cells dystrophic changes were observed in other. In addition to that, some cells were found that are considered by us to be an intermediary stage between the nondifferentiated mesenchymal cells and the fully functional Leydig cells.
- MeSH
- Leydigovy buňky ultrastruktura MeSH
- myši inbrední CBA MeSH
- myši MeSH
- otrava olovem patologie MeSH
- zvířata MeSH
- Check Tag
- mužské pohlaví MeSH
- myši MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- MeSH
- fibroblasty MeSH
- hybridomy MeSH
- imunoglobulin G MeSH
- kultivované buňky MeSH
- Leydigovy buňky ultrastruktura MeSH
- lidé MeSH
- mikrotubuly analýza MeSH
- monoklonální protilátky * imunologie MeSH
- myši MeSH
- plíce MeSH
- specificita protilátek MeSH
- tubulin analýza imunologie MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- myši MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
