Cervical total disc replacement (CTDR) aims to decrease the incidence of adjacent segment disease through motion preservation in the operated disc space. Ongoing data collection and increasing number of studies describing heterotopic ossification (HO) resulting in decreased mobility of implants, forced us to carefully evaluate our long-term clinical and morphological results of patients with CTDR. We present the first 54 consecutive patients treated with 65 ProdiscC prostheses during a 12-month period (2/2004-3/2005). All patients signed an informed consent and were included in prospective long-term study approved by hospital ethical committee. The 1- and 2-year follow-up analysis were available for all patients included and 4-year results for 50 patients (60 implants). Clinical (neck disability index-NDI, visual analog scale-VAS) and radiological follow-up was conducted at 1-, 2- and 4-years after the procedure. The Mehren/Suchomel modification of McAfee scale was used to classify the appearance of HO. Mean preoperative NDI was 34.5%, VAS for neck pain intensity 4.6 and VAS for arm pain intensity 5.0. At 1-, 2- and 4-year follow-up, the mean NDI was 30.7, 27.2, and 30.4, mean VAS for neck pain intensity 2.5, 2.1 and 2.9 and mean VAS for arm pain intensity pain 2.2, 1.9 and 2.3, respectively. Significant HO (grade III) was present in 45% of implants and segmental ankylosis (grade IV) in another 18% 4 years after intervention. This finding had no clinical consequences and 92% of patients would undergo the same surgery again. Our clinical results (NDI, VAS) are comparable with fusion techniques. Although, advanced non-fusion technology is used, a significant frequency of HO formation and spontaneous fusion in cervical disc replacement surgery must be anticipated during long-term follow-up.

• MeSH
• ankylóza etiologie   patologie   patofyziologie   MeSH
• bolest krku etiologie   patologie   patofyziologie   MeSH
• čas MeSH
• časové faktory MeSH
• diskektomie škodlivé účinky   MeSH
• dospělí MeSH
• fúze páteře škodlivé účinky   MeSH
• heterotopická osifikace etiologie   patologie   patofyziologie   MeSH
• hlava - pohyby fyziologie   MeSH
• interní fixátory škodlivé účinky   MeSH
• krční obratle patologie   chirurgie   MeSH
• lidé středního věku MeSH
• lidé MeSH
• mechanický stres MeSH
• měření bolesti MeSH
• následné studie MeSH
• pooperační komplikace etiologie   patologie   patofyziologie   MeSH
• posuzování pracovní neschopnosti MeSH
• recidiva MeSH
• rozsah kloubních pohybů fyziologie   MeSH
• výhřez meziobratlové ploténky komplikace   patologie   chirurgie   MeSH
• zatížení muskuloskeletálního systému fyziologie   MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH