OBJECTIVES: Patients suffering from rheumatoid arthritis (RA) are repeatedly affected by oral diseases or problems, including dental caries and periodontal diseases (PDs). Periodontitis and rheumatoid arthritis are chronic inflammatory destructive diseases that share many similarities. The objective of this study was to assess oral health status including examination of hard dental tissues and periodontium in patients with rheumatoid arthritis and compare the results with healthy controls. We hypothesize some interlink between oral diseases and RA. METHODS: The epidemiological case-control study involved a total of 64 subjects divided into an experimental group (14 rheumatoid arthritis cases) and a control group (50 healthy individuals). Disease activity in the subjects with RA was assessed by the Disease Activity Score (DAS28). The number of Decayed, Missing and Filled Teeth (DMFT) and Community Periodontal Index of Treatment Need (CPITN) as a basic epidemiological oral health indexes were recorded. Finally, the data were analysed statistically. RESULTS: The RA patients (19.21, SD = 6.95) showed a higher caries index level measured by DMFT than the control group (17.72, SD = 6.19); the difference was not statistically significant (U = 387.5, p = 0.547). In terms of a mean number of teeth decayed (p = 0.078), teeth filled due to caries (p = 0.397), and missing teeth (p = 0.126), the two groups were not significantly different. In terms of periodontal health, a significant difference was observed between the two groups concerning the CPI maximum score (p = 0.003). The RA patients showed higher prevalence of periodontitis than the controls. CONCLUSIONS: A complete basic oral examination, along with an oral health instruction including adequate oral and dental hygiene, is crucial to prevent dental caries and periodontal diseases and associated complications in RA patients, since they appear to be more vulnerable than the non-RA population.
- Klíčová slova
- DMFT, oral health, periodontitis, rheumatoid arthritis, tooth decay,
- MeSH
- DMF Index MeSH
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- nemoci parodontu epidemiologie MeSH
- orální zdraví * statistika a číselné údaje MeSH
- parodontální index MeSH
- revmatoidní artritida * epidemiologie komplikace MeSH
- senioři MeSH
- studie případů a kontrol MeSH
- zubní kaz epidemiologie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
AIM: Dental fear/anxiety (DFA) may considerably complicate treatment in paediatric dentistry. This cross-sectional study aimed to assess DFA in Czech preschoolers aged 3-6 years and its relationship to gender, age, location of residence, dental status and previous treatment. METHODS: The study involved 460 children from preschools in four location types selected according to the WHO criteria for oral health surveys. DFA was assessed using the Venham picture test (VPT, score range 0-8) prior to the evaluation of dental status using the dmfs (decayed, missing, filled surface) index. The significance level was set to 5%. CONCLUSION: DFA is common in Czech preschoolers. Higher levels of DFA were found in females, children aged 3-4 years, children from rural areas, children with a higher dmfs index and children who had a tooth extracted.
OBJECTIVE: The purpose of this study was to determine the prevalence and clinical effect of untreated dental caries in Roma children from eastern Slovakia using dmft/DMFT index and SiC index, association between dental caries development and oral hygiene, dietary habits and preventive dental care. METHODS: Dental caries were assessed by recording the dmft index (for primary dentition) and the DMFT index (for permanent dentition) that are used to assess the state of teeth, which expresses the current state of teeth or its development in an individual or the entire population. The SiC index was calculated as the mean dmft of one-third of the population with highest caries scores. The normality of data distribution was tested by Shapiro-Wilk test. P-value < 0.05 was considered statistically significant. Chi-square test was used to compare proportions (oral hygiene, dietary habits and preventive dental visit). Data were analysed using ordered logistic regression and t-test. The study includes questionnaire containing 5 questions about dietary habits, oral hygiene and preventive dental visit. RESULTS: The results of presented study confirmed higher average values of DMFT (3.24) in the population of 12-year-old Roma children and lower average values of dmft (2.5) in the second group (p < 0.05). The value of SiC index represented 6.10 in the group of six-year-old and 7.66 in twelve-year-old children. Logistic regression was performed to test the magnitude of the association between dental caries and related factors. There was statistically significant association between average value dmft/DMFT and dietary habits, oral hygiene, and preventive dental visit in both study groups. CONCLUSION: The study revealed insufficient oral hygiene of the Roma children population. Systematic implementation of preventive examinations for oral hygiene and health programmes are needed to promote oral health. The study represents a pilot study of the SiC index values in Roma minority population from eastern Slovakia.
- Klíčová slova
- SiC index, dental caries, dmft index, permanent dentition, primary dentition,
- MeSH
- dítě MeSH
- DMF Index MeSH
- lidé MeSH
- orální zdraví MeSH
- pilotní projekty MeSH
- prevalence MeSH
- průřezové studie MeSH
- Romové * MeSH
- zubní kaz * epidemiologie MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Slovenská republika epidemiologie MeSH
This prospective study monitored the dental status, the presence of plaque, and cariogenic microorganism levels of identical children over three years. The aim was to determine the dynamics of caries increment as well as the relationship between risk factors and caries prevalence. A total number of 125 children (72 boys and 53 girls) was included in the study, with an average age of 3.95 ± 0.06 years at the baseline. During the clinical examination at the nursery schools, the presence of dental plaque was recorded, and saliva samples were collected from the tongue of children for the DentoCult SM test providing easy detection of mutans streptococci from saliva samples. At baseline, 65.6% of the children had no caries, 4% had restored teeth with fillings or crowns or missing teeth due to caries, and 30.4% had at least one untreated caries. The percentages of intact teeth, restored or missing teeth, and untreated caries were 52.8%, 8.8%, 38.4% in the second year and 49.1%, 13.8%, and 31.1% in the third year. The dmft index value was 1.41 ± 0.24 in the first year, 2.29 ± 0.30 in the second year, and 2.33 ± 0.31 in the third year. There was a significant correlation between plaque presence and dt and dmft values (p < 0.05; the statistical analyses were performed using the Kolmogorov-Smirnov test). This 3-year longitudinal study highlighted the importance of examining both the oral hygiene and the level of cariogenic microorganisms when undertaking the evaluation of caries risk evaluation in preschool children.
- Klíčová slova
- caries increment, longitudinal study, preschool children, prospective study,
- MeSH
- DMF Index MeSH
- lidé MeSH
- longitudinální studie MeSH
- orální hygiena statistika a číselné údaje MeSH
- předškolní dítě MeSH
- prospektivní studie MeSH
- rizikové faktory MeSH
- sliny mikrobiologie MeSH
- trvalá zubní náhrada statistika a číselné údaje MeSH
- zubní kaz epidemiologie mikrobiologie MeSH
- zubní plak mikrobiologie MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- předškolní dítě MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
BACKGROUND: Matrix metalloproteinases (MMPs) play an important role in tooth formation and the mineralization of dental tissue. The aim of the study was to analyse Czech children with primary/permanent dentition polymorphisms in those genes encoding MMP2, MMP3, MMP9, MMP13, MMP16, and MMP20, which had been previously associated with dental caries in other populations. METHODS: In total, 782 Czech children were included in this case-control study. DNA samples were taken from 474 subjects with dental caries (with decayed/missing/filled teeth, DMFT ≥ 1) and 155 caries free children (DMFT = 0) aged 13-15 years, as well as 101 preschool children with early childhood caries (ECC, dmft ≥ 1) and 52 caries free children (dmft = 0), were analyzed for nine MMPs single nucleotide polymorphisms (SNPs) using real time polymerase chain reaction TaqMan assays. RESULTS: There were no significant differences in the allele and/or genotype frequencies of all the studied MMPs SNPs among children with dental caries in primary/permanent dentition and the healthy controls (P > 0.05). In addition, similar allele or genotype frequencies of the studied MMPs SNPs were found in children with severe dental caries in their permanent teeth (children with DMFT ≥ 6) and the healthy controls (DMFT = 0, P > 0.05). CONCLUSIONS: This study demonstrated the lack of association between the selected SNPs in candidate genes of MMPs and the susceptibility to or severity of dental caries in both primary and permanent dentitions in Czech children.
- Klíčová slova
- Association study, Caries, ELSPAC, Genetic predisposition, Oral disease, Polymorphism,
- MeSH
- alely MeSH
- dentice trvalá MeSH
- dítě MeSH
- DMF Index MeSH
- lidé MeSH
- mladiství MeSH
- předškolní dítě MeSH
- studie případů a kontrol MeSH
- zubní kaz * epidemiologie genetika MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- předškolní dítě MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika epidemiologie MeSH
OBJECTIVE: The aim of the study was to evaluate caries prevalence in a sample of schoolchildren aged 6 to 16 years from rural and urban areas in Croatia. METHODS: Using standardized World Health Organisation (WHO) criteria, the oral health status of 1,589 children (265 from rural and 1,324 from urban areas) was assessed by recording the following indices: DMFT (decayed, missing, filled permanent teeth), deft (decayed, extracted, filled primary teeth), DMFS (decayed, missing, filled surfaces - permanent teeth), defs (decayed, extracted, filled surfaces - primary teeth) and SiC (Significant Caries Index). Rural areas were Štitar and Babina Greda municipalities in Slavonia and urban areas were the cities of Županja (Slavonia), Zagreb and Dubrovnik. RESULTS: Half of the examined children (50.0%) had caries (D component in DMFT), with 46.0% of these being from urban and 70.2% from rural areas. The median DMFT among children was 2, 4 (rural) and 2 (urban) (p < 0.001). Among 12-year-olds, the median DMFT was 4 (rural) and 3 (urban), and mean DMFT was 3.4. The median DMFS for rural area was 5 and for urban area 3 (p < 0.001). The median deft was 1.00 for rural and 1.00 for urban, while the highest value was found among 6-year-olds at 9 in rural and 7 in urban areas. The median SiC was 4, 4 (urban) and 5 (rural). CONCLUSION: Schoolchildren from urban and rural areas in Croatia differ significantly in caries prevalence. They fall into the medium DMFT classification group according to the WHO, which indicates the need for a comprehensive oral health preservation programme.
- Klíčová slova
- DMF index, cross-sectional studies, dental caries, epidemiology, paediatric dentistry, preventive dentistry,
- MeSH
- dítě MeSH
- DMF Index MeSH
- lidé MeSH
- mladiství MeSH
- prevalence MeSH
- venkovské obyvatelstvo statistika a číselné údaje MeSH
- zubní kaz * epidemiologie MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Chorvatsko MeSH
OBJECTIVE: Dental caries is an important public health issue worldwide. In developing countries preventive dentistry is not common; hence, oral and dental health problems continue to generate serious economic and social issues. The aim of this study was to assess oral health and the incidence of dental caries in systemically healthy children aged 3-14 years, provide education on oral hygiene motivation, conduct the necessary preventive and restorative procedures, and reassess caries development at the 6-, 12-, and 18-month post-treatment follow-up. METHODS: Systemically healthy children aged 3-14 years who applied to the Paediatric Dentistry Clinic, Faculty of Dentistry, Adnan Menderes University (ADU) were included in the study. The subjects were evaluated for oral health status and incidence of dental caries based on surveys and clinical examination, motivation for oral hygiene with necessary training, completion of preventive and restorative treatments, and development of dental caries at the 6-, 12-, and 18-month post-treatment follow-up. RESULTS: The study included 320 patients, aged 3-14 years (mean age 8.08 ± 3.45 years). In children included in the study, the average decayed (d), missing (m) and filled (f) primary teeth (dmft) value was 3.81 (min-max: 0-16), decayed (D), missing (M) and filled (F) permanent teeth (DMFT) value, 1.49 (min-max: 0-6), decayed (d), missing(m) and filled(f) primary teeth surface (dmfs) value, 10.11 (min-max: 0-40), and decayed (D), missing (M) and filled (F) permanent teeth surface (DMFS) value, 2.09 (min-max: 0-12). CONCLUSIONS: For the protection and maintenance of oral and dental health in dentistry, preventive approaches should be the first concern and conservative therapeutic methods should be given priority after occurrence of any dental pathology. In addition, one-time examinations are not sufficient, and children should be examined at least twice a year. This study showed that the incidence of dental caries declined in children who underwent periodical examination and preventive dental treatment.
- Klíčová slova
- dental caries, oral hygiene, preventive dental treatment, socioeconomic level,
- MeSH
- dítě MeSH
- DMF Index MeSH
- incidence MeSH
- kojenec MeSH
- lidé MeSH
- mladiství MeSH
- orální zdraví * MeSH
- předškolní dítě MeSH
- stomatologická péče o děti * MeSH
- ukazatele zdravotního stavu * MeSH
- výsledek terapie MeSH
- zubní kaz epidemiologie prevence a kontrola MeSH
- Check Tag
- dítě MeSH
- kojenec MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- předškolní dítě MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Turecko epidemiologie MeSH
OBJECTIVES: The enamelin gene (ENAM) polymorphism (rs12640848) was recently associated with dental caries in primary teeth in Polish children. The aims of the present study were to prove this association in primary dentition and to find a possible effect of this variant on caries development in permanent dentition in Czech children. MATERIALS AND METHODS: This study comprised 905 Czech children. Totally, 187 children aged 2-6 years with primary dentition [78 healthy subjects (with decayed/missing/filled teeth, dmft = 0) and 109 patients with early childhood caries (ECC; dmft ≥ 1)] were included in this case-control study. In addition, 177 subjects aged 13-15 years without caries (DMFT = 0) and 541 children with dental caries (DMFT ≥ 1) in permanent dentition were selected from the ELSPAC study. Genotype determination of the ENAM polymorphism (rs12640848) was based on the TaqMan method. RESULTS: No significant differences in the allele or genotype frequencies between the caries-free children and those affected by dental caries were observed in both primary and permanent dentitions. CONCLUSIONS: Lack of association between the ENAM polymorphism (rs12640848) and dental caries in Czech children was detected. CLINICAL RELEVANCE: Although ENAM is considered as a candidate gene for dental caries, the presence of the ENAM variant (rs12640848) cannot be used as a risk factor of this multifactorial disease in the Czech population.
- Klíčová slova
- Case-control study, Dental caries, Enamelin, Gene polymorphism, Permanent dentition, Primary dentition,
- MeSH
- dentice trvalá MeSH
- dítě MeSH
- DMF Index MeSH
- extracelulární matrix - proteiny genetika MeSH
- genotyp MeSH
- jednonukleotidový polymorfismus * MeSH
- kojenec MeSH
- lidé MeSH
- mladiství MeSH
- předškolní dítě MeSH
- zubní kaz epidemiologie genetika MeSH
- zuby mléčné MeSH
- Check Tag
- dítě MeSH
- kojenec MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- předškolní dítě MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Česká republika epidemiologie MeSH
- Názvy látek
- ENAM protein, human MeSH Prohlížeč
- extracelulární matrix - proteiny MeSH
AIM: We analyzed the VDR TaqI (rs731236) gene polymorphism in children with and those without dental caries. METHODS: A total of 388 subjects, 153 caries-free (with decayed/missing/filled teeth [DMFT] = 0) and 235 children with dental caries (DMFT ≥1), were genotyped by the TaqMan method. RESULTS: Although no significant differences in VDR TaqI allele and genotype frequencies between caries-free and caries-affected children were detected, a significant association between this polymorphism and gingivitis was found (p < 0.05). CONCLUSIONS: In contrast to previous studies from China and Turkey, the VDR TaqI gene variant cannot be used as a marker for identification of Czech children with increased dental caries risk.
- MeSH
- alely MeSH
- DMF Index MeSH
- genetická predispozice k nemoci genetika MeSH
- genetické asociační studie MeSH
- genotyp MeSH
- gingivitida epidemiologie genetika MeSH
- jednonukleotidový polymorfismus * MeSH
- lidé MeSH
- mladiství MeSH
- odds ratio MeSH
- receptory kalcitriolu genetika MeSH
- restrikční endonukleasy typu II MeSH
- studie případů a kontrol MeSH
- zubní kaz epidemiologie genetika MeSH
- Check Tag
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika epidemiologie MeSH
- Názvy látek
- receptory kalcitriolu MeSH
- restrikční endonukleasy typu II MeSH
- TCGA-specific type II deoxyribonucleases MeSH Prohlížeč
- VDR protein, human MeSH Prohlížeč
The aim of this study was to analyze the association between BMP2 (rs1884302) and DLX3 (rs2278163) gene polymorphisms and dental caries in primary and permanent dentitions. A total of 914 subjects were genotyped by the TaqMan methods: 176 caries-free children (with Decayed/Missing/Filled Teeth, DMFT = 0), 542 patients with dental caries in permanent dentition (DMFT ≥1), 83 caries-free children with primary teeth (with decayed/missing/filled teeth, dmft = 0), and 113 children with early childhood caries (ECC, dmft ≥1). There were no significant differences in allele/genotype frequencies between patients with caries in permanent dentition/ECC and caries-free children or between patients with very low (DMFT = 0-2), low (DMFT = 3-5), moderate (DMFT = 6-8), or high (DMFT ≥9) caries experience. Variability in BMP2 and DLX3 was not associated with caries in the Czech population.
- Klíčová slova
- BMP2, Case-control study, DLX3, Dental caries, Gene polymorphism,
- MeSH
- alely MeSH
- dentice trvalá MeSH
- dítě MeSH
- DMF Index MeSH
- genetická predispozice k nemoci MeSH
- genotyp MeSH
- homeodoménové proteiny genetika MeSH
- jednonukleotidový polymorfismus * MeSH
- kostní morfogenetický protein 2 genetika MeSH
- lidé MeSH
- mladiství MeSH
- předškolní dítě MeSH
- stupeň závažnosti nemoci MeSH
- transkripční faktory genetika MeSH
- zubní kaz genetika MeSH
- zuby mléčné MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- předškolní dítě MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika MeSH
- Názvy látek
- BMP2 protein, human MeSH Prohlížeč
- Distal-less homeobox proteins MeSH Prohlížeč
- homeodoménové proteiny MeSH
- kostní morfogenetický protein 2 MeSH
- transkripční faktory MeSH
