Southern hybridization with probes designed for detection of WD-repeats coding sequences gave positive results in 21 streptomycete strains indicating that WD-repeats encoding genes are massively spread among streptomycetes. One of them, the wdlA gene of Streptomyces lincolnensis, codes for a 971 amino acid protein with seven WD-repeats in its C-terminus, two transmembrane domains and an ATP/GTP binding site upstream of the WD-repeat region.

• MeSH
• ATP-Binding Cassette Transporters genetics   MeSH
• Bacterial Proteins genetics   metabolism   MeSH
• DNA Probes MeSH
• Cloning, Molecular MeSH
• Membrane Proteins genetics   MeSH
• Molecular Sequence Data MeSH
• GTP-Binding Proteins genetics   MeSH
• Repetitive Sequences, Amino Acid genetics   physiology   MeSH
• Amino Acid Sequence MeSH
• Sequence Analysis, DNA MeSH
• Sequence Alignment MeSH
• Blotting, Southern MeSH
• Streptomyces genetics   growth & development   MeSH
• Publication type
• Journal Article MeSH
• Research Support, Non-U.S. Gov't MeSH
• Names of Substances
• ATP-Binding Cassette Transporters MeSH
• Bacterial Proteins MeSH
• DNA Probes MeSH
• Membrane Proteins MeSH
• GTP-Binding Proteins MeSH
• wdlA protein, Streptomyces lincolnensis MeSH Browser