The cellular immune response (MIF, E-rosette formation and changes in nucleolar morphology of lymphocytes) was followed as related to age and antigenic stimulation. MIF in healthy infants increased from the 2nd to the 12th week of life as compared with the first week, probably due to BCG vaccination. The total and active E-rosette formation did not change during the whole period of investigation. Ring-shaped nucleoli increased gradually from the second week of life. Active nucleoli increased up to the 4th week, i.e. after BCG vaccination and then slowly decreased. Micronucleoli being high in the first week, decreased during 24 weeks of life. After artificial colonization of the intestine the production of MIF was slightly lower in colonized infants than in controls from the 2nd to the 12th week. The other parameters followed were not influenced by colonization.

• MeSH
• BCG vakcína imunologie   MeSH
• buněčná imunita * MeSH
• buněčné jadérko ultrastruktura   MeSH
• Escherichia coli růst a vývoj   MeSH
• inhibiční faktory migrace leukocytů biosyntéza   MeSH
• kojenec MeSH
• lidé MeSH
• lymfocyty imunologie   ultrastruktura   MeSH
• lymfokiny biosyntéza   MeSH
• novorozenec MeSH
• střeva mikrobiologie   MeSH
• tvorba rozet * MeSH
• vakcinace MeSH
• Check Tag
• kojenec MeSH
• lidé MeSH
• novorozenec MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• BCG vakcína MeSH
• inhibiční faktory migrace leukocytů MeSH
• lymfokiny MeSH