Protoplast formation, stabilization and regeneration was improved for 4 strains (erythromycin producers) of Saccharopolyspora erythraea. A modified medium was developed for protoplast regeneration. Parental and protoplast-regenerated strains exhibited changes in morphology, ultrastructure, and antibiotic production.

• MeSH
• Erythromycin biosynthesis   MeSH
• Culture Media MeSH
• Microscopy MeSH
• Protoplasts * MeSH
• Industrial Microbiology * MeSH
• Saccharopolyspora genetics   growth & development   metabolism   ultrastructure   MeSH
• Microscopy, Electron, Transmission MeSH
• Publication type
• Journal Article MeSH
• Names of Substances
• Erythromycin MeSH
• Culture Media MeSH