BACKGROUND: Lumbosacral plexopathy caused by radiotherapy is a rare but severe consequence of cancer treatment. This condition often leads to varying degrees of sensory and motor impairment. Neurological complications, which are typically permanent, manifest a long period after irradiation. CASE PRESENTATION: We describe a case of progressive lower extremity weakness and sensory impairment in a woman who had been effectively treated with radiotherapy for cervical cancer with development 36 years after irradiation. The electrophysiological assessment revealed a subacute bilateral axonal lesion of the lumbosacral plexus. None of the clinical manifestations, serology, cerebrospinal fluid or imaging data discovered an explanation other than radiation-induced lumbosacral plexopathy (RILP). CONCLUSIONS: This case demonstrates that RILP may emerge more than 30 years after the radiotherapy.

• Keywords
• Case report, Cervical cancer, Lumbosacral plexus, Radiation-induced lumbosacral plexopathy, Radiotherapy,
• MeSH
• Diagnostic Imaging MeSH
• Humans MeSH
• Uterine Cervical Neoplasms * radiotherapy   pathology   MeSH
• Lumbosacral Plexus pathology   MeSH
• Multiple Trauma * pathology   MeSH
• Radiation Injuries * etiology   pathology   MeSH
• Check Tag
• Humans MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Case Reports MeSH