BACKGROUND: The aim of our study was to assess changes of tear film osmolarity after micro-incision 25G+ pars plana vitrectomy (PPV) in a prospective study. METHODS: The group consisted of 21 patients (17 women, 4 men) with an average age of 70,52 years [48; 85]. All patients underwent 25G + PPV surgery due to a disorder of the vitreomacular interface (macular hole or epimacular membrane). Only patients who did not use artificial tears before the surgery and who had not been diagnosed with dry eye syndrome at ours or another institution were included in the study. Except cataract surgery, all ocular surface diseases, intraocular diseases, trauma or surgery were exclusion criterias. Tear film osmolarity was measured in both eyes in every patient before surgery, 10 days after surgery and 30 days after surgery. A paired test was used for statistical evaluation. RESULTS: No statistically significant change in osmolarity was found in the operated eyes (p > 0.05). No statistically significant changes in time (p > 0.05) were found when both eyes were compared. There were no postoperative complications or failure to observe the study protocol. CONCLUSION: Micro-incision 25G + PPV does not affect the osmolarity of the tear film.

• Keywords
• Anterior segment, Ocular surface disease, Osmolarity, Pars plana vitrectomy, Tear film,
• MeSH
• Humans MeSH
• Osmolar Concentration MeSH
• Prospective Studies MeSH
• Aged MeSH
• Tears MeSH
• Dry Eye Syndromes * MeSH
• Vitrectomy * MeSH
• Check Tag
• Humans MeSH
• Male MeSH
• Aged MeSH
• Female MeSH
• Publication type
• Journal Article MeSH