Nejvíce citovaný článek - PubMed ID 32460506
Pharmacokinetic aspects of beta-lactam antibiotic therapy in intensive care unit patients: A one-center experience with TDM
The aim of this article is to demonstrate extreme interindividual variability of piperacilin/tazobactam (PIP/TAZO) pharmacokinetics in critically ill morbidly obese patients and to emphasize the need for the practice of routine PIP/TAZO plasma concentrations measurement in order to ensure optimal efficacy and safety of antibiotic therapy.
- Klíčová slova
- critical illness, morbid obesity, piperacillin/tazobactam (PIP/TAZO), therapeutic drug monitoring (TDM),
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH