Nejvíce citovaný článek - PubMed ID 330367
Antifungal antibiotic of the Basidiomycete Oudemansiella mucida. III. Nuclei in the hyphae of mono- and dikaryons
Basidiospores of Agrocybe cylindracea were found to be viable for 12 years, those of Oudemansiella mucida for 6 years. The ability of monosporic isolates from these spores to produce antibiotics has been partly preserved.
- MeSH
- antibakteriální látky biosyntéza MeSH
- Basidiomycota růst a vývoj metabolismus fyziologie MeSH
- časové faktory MeSH
- spory hub MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- antibakteriální látky MeSH
Mutants of Oudemansiella mucida, blocked in the biosynthesis of the antibiotic mucidin, were obtained at a 0.28% frequency after the application of N-methyl-N'-nitro-N-nitrosoguanidine (MNG) to basidiospores under conditions leading to 0.5--5.0% survival rates. Loss of antibiotic activity was in most isolates accompanied by a decrease in mycelium growth rate and a suppression of dikaryotizing and fructification ability. Recombination analysis of two stable mutants revealed that the block in mucidin synthesis is the result of mutation in the same chromosomal gene (muc). In contrast to the action of MNG, UV-irradiation leads neither to the loss of biosynthetic activity nor to any morphological change.
- MeSH
- Agaricales genetika metabolismus fyziologie MeSH
- antibakteriální látky biosyntéza MeSH
- geny * MeSH
- křížení genetické MeSH
- methakryláty MeSH
- methylnitronitrosoguanidin MeSH
- mutace MeSH
- nenasycené mastné kyseliny MeSH
- strobiluriny MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- antibakteriální látky MeSH
- methakryláty MeSH
- methylnitronitrosoguanidin MeSH
- mucidin MeSH Prohlížeč
- nenasycené mastné kyseliny MeSH
- strobiluriny MeSH