Factor Ei isolated from Listeria monocytogenes caused in rabbits 1 d after intravenous administration activation of peripheral blood lymphocytes in terms of rRNA biosynthesis. Increase of the number of these active lymphocytes was observed not only in peripheral blood, but also in spleen, lung, kidney, and liver. when the number of lymphocytes was related to the amount of the organ tissue cells, the increment appeared significant only in the liver where the number of active lymphocytes exceeded the control value by one order of magnitude. Based upon this observation we concluded that the accumulation of Listeria factor Ei activated lymphocytes occurred in liver. This characteristic is considered an additional immunomodulative property of Listeria factor Ei similar to the Escherichia coli lipopolysaccharide.

• MeSH
• aktivace lymfocytů účinky léků   MeSH
• biologické faktory imunologie   farmakologie   MeSH
• játra imunologie   MeSH
• králíci MeSH
• ledviny imunologie   MeSH
• Listeria monocytogenes imunologie   MeSH
• počet lymfocytů účinky léků   MeSH
• podskupiny lymfocytů účinky léků   imunologie   MeSH
• slezina imunologie   MeSH
• zvířata MeSH
• Check Tag
• králíci MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Názvy látek
• biologické faktory MeSH
• Listeria monocytogenes factor Ei MeSH Prohlížeč