The aim of this research was to evaluate mutual interchangeability of four principally different biometric instrumental techniques designed for objective measurement of changes in the physical, mechanical, and topographical properties of the skin surface treated with commercial antiaging cosmetic products with hyaluronic acid. The following instrumental devices were used: Visioscope PC 35, Corneometer Multiprobe Adapter MPA 6, Reviscometer RVM 600, and 3D scanner Talysurf CLI 500. The comparison of the individual methods was performed using cluster analysis. The study involved 25 female volunteers aged 40-65. Measurements were taken before and after 30 daily in vivo applications of an antiaging preparation to the skin surface in the periorbital area. A slight reduction in skin surface roughness was recorded in 55% of the volunteers. On the contrary, a worsening from their initial states was detected in 25% of the subjects, while for 20%, no significant change was reported. Cluster analysis confirmed that the mentioned methodologies can be divided into two basic clusters, namely, a cluster of methods recording the changes in skin relief by means of optical techniques, and a cluster of methods investigating changes in hydration and anisotropy. In practice, the techniques in different clusters are not interchangeable and should be assessed separately.

• MeSH
• biometrie metody   MeSH
• chemické jevy * MeSH
• dospělí MeSH
• kosmetické přípravky aplikace a dávkování   MeSH
• kůže účinky léků   MeSH
• kyselina hyaluronová aplikace a dávkování   MeSH
• lidé středního věku MeSH
• lidé MeSH
• povrchové vlastnosti * MeSH
• viskosuplementy aplikace a dávkování   MeSH
• zdraví dobrovolníci pro lékařské studie MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• kosmetické přípravky MeSH
• kyselina hyaluronová MeSH
• viskosuplementy MeSH