INTRODUCTION: Papillary carcinoma is the most frequent malign tumour of the thyroid with rising incidence and metastasising in lymphatic veins. AIM: Diagnosing our patients and comparing the TNM stages to metastases found in lymphatic nodes. MATERIALS, METHODS: A retrospective study of 1,353 patients treated at our department between 2005 and 2008. RESULTS: 220 (16.3%) malign thyroid tumours have been found among 1,353 patients. Papillary carcinoma has been found in 180 cases, according to the TNM classification T1 mic 80x (44.4%), T1 58x (32.2%), T2 29x (16.1%), T3 8x (4.4%), T4 5x (2.8%). Multifocal incidence of papillary carcinoma has been observed in 42 patients (23.3%). Lymphadenectomy cervicocentral 18x, ipsicervicolateral 52x, contracervicolateral 1x. In total, 351 nodes were removed and 113 nodes had metastasis of papillary carcinoma. 2 patients had permanent paresis of the NLR (1.11%), nerve at risk 0.56%, transitory paresis 5.56%. CONCLUSION: The basic surgical treatment of the thyroid with papillary carcinoma is total thyroidectomy with cervicocentral lymphadenectomy. Ipsilateral lympadenectomy is indicated in the case of nodes found sonographically or tumour size T2.
- MeSH
- dospělí MeSH
- krk MeSH
- lidé středního věku MeSH
- lidé MeSH
- lymfadenektomie * MeSH
- mladiství MeSH
- mladý dospělý MeSH
- nádory štítné žlázy patologie chirurgie MeSH
- papilární karcinom patologie chirurgie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- tyreoidektomie * MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
AIM: In the management of early breast carcinoma, biopsy of sentinel lymph nodes has gradually replaced dissection of Level I and II axillary nodes. The aim of the study is to assess feasability and reliability of the method in our conditions. METHOD: From June 1998 to June 2007, a total of 458 sentinel node biopsies (SLNB) were performed. Originally, patent blue sentinel node mapping was used. Since 2000, a combination of radiocolloid application and a gamma- probe (detector), as well as the patent blue, has been used. Originally, SLNBs were followed by axillary dissections, however, in 2002, the procedure was waived in cases of negative sentinel nodes findings. RESULTS: Out of the total of 458 SLNB patients, 382 female patients were included in the study. SLNB, without concomitant axillary dissection, was performed in 170 subjects. In 70 subjects, the sentinel node was positive and they were indicated for axillary dissections. Positive non-sentinel nodes were detected 17 times. In total, 899 sentinel nodes were examined in the study group of 382 biopsies. The mean was 2.35. False negative nodes were recorded in three cases in female patients with SLNB and axillary dissection (4.6%). No local relapses in the axilla were recorded in negative sentinel node findings without subsequent axillary dissections. CONCLUSION: Sentinel node biopsy is a safe alternative to axillary dissection in the surgical management of early breast carcinoma.
- MeSH
- axila MeSH
- barvicí látky MeSH
- biopsie sentinelové lymfatické uzliny * MeSH
- dospělí MeSH
- falešně negativní reakce MeSH
- lidé středního věku MeSH
- lidé MeSH
- lymfadenektomie MeSH
- lymfatické uzliny MeSH
- nádory prsu patologie chirurgie MeSH
- radiofarmaka MeSH
- rosanilinová barviva MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- technecium 99mTc-agregovaný albumin MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- barvicí látky MeSH
- radiofarmaka MeSH
- rosanilinová barviva MeSH
- sulfan blue MeSH Prohlížeč
- technecium 99mTc-agregovaný albumin MeSH
- technetium Tc 99m nanocolloid MeSH Prohlížeč