We present a case of a young 26-year-old woman, who has been suffering from localised scleroderma (morphea) for 15 years. Recently, a lesion on the dorsum of her right foot ulcerated. Based on a CT scan and X-ray a diagnosis of ulcerative osteomyellitis was established. The patient was treated with a combination of antibiotics. Subsequent histological examinations showed granulomatous tissue and chronic inflammatory changes on top of pseudoepiteliomatous hyperplasia. The patients status was deteriorating, which resulted in a limb amputation under the knee. Three months later, there was a metastasis of squamous cell carcinoma found in the patients inguinal lymph node. In spite of combined therapy (surgery, radioterapy and systemic chemotherapy), new metastases occurred and the patient succumbed to the disease several months afterwards. The case was concluded as a squamous cell carcinoma camouflaged by osteomyelitis. Malignant turn of localised sclerodema is very rare. It usually occurs on the lower extremities of patients with a long course of the disease and is associated with pansclerotic or generalised variants of morphea.

• MeSH
• amputace MeSH
• antibakteriální látky terapeutické užití   MeSH
• dospělí MeSH
• fatální výsledek MeSH
• lidé MeSH
• lokalizovaná sklerodermie komplikace   MeSH
• lymfatické metastázy MeSH
• nádory kůže etiologie   terapie   MeSH
• osteomyelitida diagnostické zobrazování   terapie   MeSH
• radiografie MeSH
• spinocelulární karcinom etiologie   terapie   MeSH
• vředy na noze (od hlezna dolů) etiologie   terapie   MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• kazuistiky MeSH
• Názvy látek
• antibakteriální látky MeSH