AIM OF THE STUDY: Aim of the study was to investigate connection between the level CA125, level of haemoglobin and emergence of recurrence and survival time for patients with ovarian cancer. MATERIAL AND METHODS: This concerns of retrospective study in which total 53 patients with histology confirmed ovarian cancer were included. These patients were diagnosed and subsequently treated in the GPK FN MU Brno during 2000-2002 period. RESULTS: The level of CA125 in our study appeared to be statistically significant prognostic factor (beta = 0.44, p = 0.02) for survival. Signification of the plasma level of haemoglobin to be any prognostic factor was not proved in this study. Among other assessed factors influencing survival time of the patients was the number of gravidity to be important prognostic factor (beta = -0.96, p = 0.002). Survival time was shorter for patients with less number of pregnancies. CONCLUSION: Ovarian cancer is tumour with high mortality. That is why it is necessary to look for new markers, which would contribute to earlier diagnostic of this disease, and which could influence its prognosis.

• MeSH
• antigen CA-125 krev   MeSH
• dospělí MeSH
• hemoglobiny analýza   MeSH
• karcinom diagnóza   MeSH
• lidé středního věku MeSH
• lidé MeSH
• míra přežití MeSH
• mladý dospělý MeSH
• nádorové biomarkery krev   MeSH
• nádory vaječníků diagnóza   mortalita   MeSH
• prognóza MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladý dospělý MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH
• Názvy látek
• antigen CA-125 MeSH
• hemoglobiny MeSH
• nádorové biomarkery MeSH