BACKGROUND: The aim of the study was to compare health-related quality of life (QoL) and oncological outcome between gynaecological cancer patients undergoing pelvic exenteration (PE) and extended pelvic exenteration (EPE). EPEs were defined as extensive procedures including, in addition to standard PE extent, the resection of internal, external, or common iliac vessels; pelvic side-wall muscles; large pelvic nerves (sciatic or femoral); and/or pelvic bones. METHODS: Data from 74 patients who underwent PE (42) or EPE (32) between 2004 and 2019 at a single tertiary gynae-oncology centre in Prague were analysed. QoL assessment was performed using EORTC QLQ-C30, EORTC CX-24, and QOLPEX questionnaires specifically developed for patients after (E)PE. RESULTS: No significant differences in survival were observed between the groups (P > 0.999), with median overall and disease-specific survival in the whole cohort of 45 and 49 months, respectively. Thirty-one survivors participated in the QoL surveys (20 PE, 11 EPE). No significant differences were observed in global health status (P = 0.951) or in any of the functional scales. The groups were not differing in therapy satisfaction (P = 0.502), and both expressed similar, high willingness to undergo treatment again if they were to decide again (P = 0.317). CONCLUSIONS: EPEs had post-treatment QoL and oncological outcome comparable to traditional PE. These procedures offer a potentially curative treatment option for patients with persistent or recurrent pelvic tumour invading into pelvic wall structures without further compromise of patients ́ QoL.
- MeSH
- exenterace pánve * metody MeSH
- kvalita života MeSH
- lidé MeSH
- nádory pánve * chirurgie MeSH
- průzkumy a dotazníky MeSH
- retrospektivní studie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Publikační typ
- abstrakt z konference MeSH
Early diagnosis of an infected vascular prosthesis, a potentially life-threatening disease, is a precondition of adequate treatment. The most frequently used diagnostic imaging method is computer tomography. Non-acute infections caused by low grade agents may pose a challenge with ambiguous CT-images and other ancillary imaging methods are used for these cases, each offering different levels of diagnostic sensitivity. These methods come from the fields of radiology (magnetic resonance imaging - MRI) and nuclear medicine studies using labelled leukocytes (111In or 99mTc HMPAO), 99mTc labelled antigranulocyte antibodies, 67Ga-citrate or labelled antibiotics (99mTc-ciprofloxacin) or avidin in combination with 111In-biotin. Positron emission tomography (PET) or hybrid PET/CT using 18F-FDG are becoming increasingly popular. The authors of this review article point out the diagnostic potential of the different methods and current trends, including the possibilities of microbiological demonstration of the agent, as well as their potential position in the diagnostic algorithm.
- MeSH
- cévní protézy škodlivé účinky MeSH
- citráty diagnostické užití MeSH
- galium diagnostické užití MeSH
- infekce spojené s protézou diagnóza mikrobiologie ultrasonografie MeSH
- lidé MeSH
- magnetická rezonanční tomografie MeSH
- multimodální zobrazování MeSH
- radioizotopy galia diagnostické užití MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
- MeSH
- arteria brachialis zranění MeSH
- autologní transplantace metody využití MeSH
- chirurgie operační metody využití MeSH
- dospělí MeSH
- lidé MeSH
- loket MeSH
- poranění lokte MeSH
- vény transplantace MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
Představujeme případ pacienta s ilikofemorální rekonstrukcí vlastní velkou safenou. Indikací před 21 roky bylo poranění pánevní tepny při polytraumatu. Bypass byl 20 let průchodný s postupnou arterializací graftu. Nadměrná dilatace byla příčinou uzávěru rekonstrukce. Ischemie LDK byla řešená implantací ilico-femorálního crossover bypassu.
We present the case of patient with autovenous ilicofemoral bypass after 21 years. The indication was traumatic demage of left iliac artery during car accident. The arterial reconstruction was patent for more than two decades with gradual arterialisation of graft. Excessive dilatation has caused the late occlusion of bypass. Ischaemia of the left limb was treated by crossover ilico-femoral bypass.
