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Evaluation of certain veterinary drug residues in food : fifty-eight report of the joint FAO/WHO Expert Committee on Food Additives

Publikováno
Geneva : WHO, 2002
Edice
WHO technical report series, ISSN 0512-3054 911
Stránkování
v, 66 s. : tab. ; 24 cm

Jazyk angličtina Země Švýcarsko

Typ dokumentu publikace WHO

Perzistentní odkaz   https://www.medvik.cz/link/MED00097619
Odkazy

Knihovny.cz ISBN 92-4-120911-9

This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of veterinary drugs within the terms of reference of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), including a hypothesis-driven decision tree approach for the safety evaluation of residues of veterinary drugs; comments on the Committee for Veterinary Products for Medicinal Use reflection paper on the new approach developed by JECFA for exposure and maximum residue limit (MRL) assessment of residues; residues of veterinary drugs in honey and possible approaches to derive MRLs for this commodity; comments on a paper entitled “Risk-assessment policies: Differences among jurisdictions”; and the use of no-observed-effect level (NOEL) and no-observed-adverse-effect level (NOAEL) in JECFA assessments. Summaries follow of the Committee’s evaluations of toxicological and residue data on a variety of veterinary drugs: three antimicrobial agents (avilamycin, tilmicosin, tylosin), one authentic (triclabendazole), one production aid (melengestrol acetate), two antimicrobial agents and production aids (monesin and narasin), a glucocorticosteroid (dexamethasone) and an antimicrobial agent ands contaminant (malachite green). Annexed to the report is a summary of the Committee’s recommendations on these drugs, including acceptable daily intakes (ADI’s) and proposed MRL’s.

"A meeting of the joint FAO/WHO Expert Committee on Food Additives was held at Food and Agriculture Organization of the United Nations (FAO) Headquarters, Rome, from 21 to 27 February 2002."

Bibliografie atd.

Literatura: s. 50-52

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