Aimed at all researchers into human development and the wider medical research audience, this text brings together various strands of the discipline of the molecular genetics of early human development, and provides examples of the approaches being used. Human development disorders are a significant clinical burden and should ideally be investigated by the study of normal human embryos. However, the studies have been hampered by the lack of material and by public sensitivities. Much reliance has been placed on extrapolating data from mouse embryos, but there is an increased awareness of fundamental differences between the mouse and human genomes.

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