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Endothelin and its inhibitors

Edited by Timothy D. Varner, Contributor B. Battistini

Publikováno
Berlin : Springer-Verlag, 2001
Edice
Handbook of experimental pharmacology, ISSN 0171-2004 Vol. 152
Stránkování
xxiv, 532 s. : il.

Jazyk angličtina Země Německo

Typ dokumentu příručky

Perzistentní odkaz   https://www.medvik.cz/link/MED00143267
Odkazy

Knihovny.cz ISBN 3-540-67985-5

Recent publications have addressed specific aspects of the endothelins, such as their roles in disease or the importance of endothelin receptors. However, in this book the entire field of endothelins is covered. This includes the pathways of endothelin production and their regulation, the local and systemic actions of endothelins, receptors for the endothelins and the signalling pathways employed, and the involvement of endothelins in a range of diseases. Attention is also paid to the development through chemistry, pharmacology and toxicology of endothelin antagonists and endothelin-converting enzyme inhibitors, with mention of all the important members of these drug classes. This leads to well-rounded discussions of the potential therapeutic benefit of endothelin inhibitors.

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